Richard
S. Pollenz, Ph.D.
Associate Professor in the Department of Biology
E-mail:
pollenz@chuma1.cas.usf.edu
Phone: 813-974-1596
Web page: http://www.cas.usf.edu/biology/index.html
Training
B.S.: University of the Sciences Philadelphia (USP), Toxicology, 1983 Ph.D.:
Northwestern University, Cell Molecular Biology, 1991
Postdoctoral Fellow: McArdle Cancer Center, Univ. of Wisconsin, 1991-1994.
Assistant Prof., Medical University of South Carolina, 1994-1990. Associate Prof., Medical University of South Carolina, 1999-2000.
Research
Interests
Our overall focus is to better understand the response of organisms to
environmental stress at the molecular level. The stresses of interest
are chemical contaminants (halogenated aromatic hydrocarbons, typified
by 2,3,7,8-tetrachlorodibenzo-p-dioxin, TCDD) and low oxygen (hypoxia).
The models of interest include both aquatic and mammalian species with
emphasis on the Ah receptor and hypoxia signal transduction systems. These
pathways have wide ranging impact in cancer, development and reproduction.
Search
for publications by: 
This
search will be conducted at the US National Library of Medicine (NLM) and PubMed.
Selected
Publications
Necela, B., and Pollenz, R.S. 1999. Functional analysis of activation
and represssion domains with the rainbow trout ARNT protein Biochemical
Pharmacology 57:1177-1190.
Davarions, N.A. and Pollenz, R.S. 1999. Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytoplasmic proteasome following nuclear export. J. Biol. Chem. 274:28708-28715.
Pollenz R.S., N.A. Davarinos, and T.P. Shearer. 1999 Analysis of AHR-mediated signaling under physiological hypoxia reveals lack of competition for the ARNT transcription factor. Molecular Pharm. 56:1127-1137.
Heid, S.E., Pollenz R.S, and Swanson H.I. 2000. Role of heat shock protein 90 in mediating agonist-induced activation of the aryl hydrocarbon receptor. Molecular Pharm. 57:82-92
Pollenz, R.S., and Barbour, E.R. 2000 Analysis of the complex relationship between nuclear export and Ah receptor-mediated gene regulation. Mol. Cell. Biol. 20-6094-6105.
Cancer Biology Ph.D. Program
H. Lee Moffitt Cancer Center, MRC-4 East
12902 Magnolia Drive
Tampa, Florida 33612
Phone: 813-745-6876
E-mail: CancerPHD@moffitt.org
Copyright © 2000 University of South Florida